How Can You Prevent and Treat Thrombosis

The formation of a blood clot in a vein, artery or heart, thrombosis is usually caused by damage to the lining of the blood vessel. Other causes are blood clotting and an increased tendency to clot in the blood.

Damage to the blood vessel wall causes blood platelets to stick together and release prothrombin, a substance that causes fibrin strands. put these threads become entangled with blood cells and a clot or thrombus is formed.

Damage to veins is usually due to inflammation; the damage to the arteries is from atherosclerosis; and damage to the lining the heart is from a heart attack in which the damage to the heart muscle (infarct) extends to the interior of the heart.

The danger of thrombosis lies in the threat of circulation: a clot may block the artery and cut off the blood supply. tissue, such as the heart or brain (infarction) or become detached and swept away in the blood stream to a distant artery and blocked (embolism).

A pile of thrombosis, or haemorrhoid, is painful, but not dangerous. Thrombosis in varicose veins can be curative; In the treatment of varicose veins by infusion, the injected substance irritates the lining of the vein, causing thrombosis and the destruction of the unwanted varicose vein. But thrombosis in an artery supplying a vital organ is serious; it is heavy; A clot in a cerebral artery causes a stroke and one in a coronary artery causes a heart attack.

Sometimes a heart attack heart or cardiac infarction is followed by the development of a blood clot in the damaged inner wall of the heart. Such a clot can break off and travel to the brain (an uncommon cause of stroke). If the clot is separated in the deep veins, it will be carried to the lungs (pulmonary embolism); pain, sighs, even death.

Prevention of thrombosis in the artery is based on these measures to avoid atherosclerosis including regular exercise, no smoking, and control of older than 35 and female smokers older than 30 are at even greater risk and are advised to use another method. contraception

The prevention of thrombosis after surgical operations has been based for many years on the principle of leaving the patient’s bed early to combat the stagnation of blood in the veins of the leg. It has recently been shown that the risk of thrombosis is greatly reduced by small injections of the anticoagulant heparin and by intermittent compressions of the calf muscles.

To prevent thrombosis after a heart attack, sulphinpyrazone can be recommended, and in some serious cases, the oral anticoagulant warfarin. This drug is also given with dipyridamole to patients with artificial heart valves to prevent clots from forming in foreign implants. However, treatment with warfarin requires regular blood tests to determine the right dose and flow of drugs that alter it. its effect. One such drug is aspirin, which has a mild anticlotting action in preventing minor strokes (transient cerebral ischemia).

Treatment of thromboembolism is with rapid-acting heparin, intravenously for a week or so and for several months followed by therapeutic tablets. Other drugs have been used that destroy fibrin, rapid-acting fibrotic thromboembolism with heparin, given intravenously for a week and followed by wartime tablets for several months. Other drugs should be used that break down fibrin, fibrinolytic agents such as streptokinase and urokinase; They dissolve the new thrombus injected into the affected vessel.

Source:

Journal of thrombosis and haemostasis

Volume 7, Number 12, December 2006, pp

Publisher: Blackwell Publishing

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