Ectopic Neuroendocrine Tumors & Cushing’s Syndrome

Complications of the endocrine system affect millions of adults each year. While many complications can be prevented, those people who suffer from endocrine disorders have genetic or hereditary complications. Endocrine tumors are complications that can prevail over genetic complications and those who suffer from an acquired endocrine disorder.

Endocrine tumors are often misdiagnosed. Without proper diagnosis and treatment, some endocrine disorders can lead to syndromes that reduce the quality of life and affect long-term health. In the case of ectopic endocrine tumors, while rare, it is possible to develop a complication Cushing syndrome. Given the malignancy in the mesentery, if you suffer from ectopic endocrine tumors that are malignant in nature, it is important to talk to your healthcare professional about your long-term risk for Cushing’s syndrome.

As a form of treatment, your doctor will most likely recommend a thyroidectomy. Your treatment plan, along with managing your endocrine malignancy and the risks of Cushing’s syndrome, involves managing and reversing hypercortisolism. In addition to thyroidectomy, your doctor may also recommend the removal of any potential pituitary lesions. Due to the continuous risk for developing damage throughout the body’s systems, the presence of neuroendocrine tumors must be closely and effectively treated, once diagnosed.

Measuring cortisol levels through urine tests is an effective tool to determine if neuroendocrine complications are well controlled. In addition, surgical removal of your neuroendocrine tumor is necessary and then regular CT scans to determine if a health complication has resulted in the growth of ectopic endocrine tumors. In some cases, chemotherapy and radiation therapy will be effective and provide some degree of recovery from the endocrine complication and progression of Cushing’s syndrome.

Complications involving endocrine are quite common. However, complications arising from ectopic endocrine tumors are not so common and, as a result, are often misdiagnosed. Without a proper diagnosis, a malignant complication can occur, resulting in the development of lesions through other bodily forms. When a developmental lesion leads to adverse complications in the thyroid and pituitary, for example, surgical removal of those lesions will be necessary. Because of the long-term effects of Cushing’s syndrome, an early diagnosis of this type of rare endocrine disorder is important for long-term health and the resolution of possible secondary health complications.

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